提供高品质卡瓦提取物
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- 长沙捷凯生物制品有限公司 商铺
- 认证
- 报价
- 请来电询价
- 主要成分
- Kavlactones
- 提取来源
- 卡瓦根
- 外观
- 浅黄至浅棕黄色
- 所在地
- 中国 湖南 长沙市 人民东路111号长房东郡13栋3门1106室
- 联系电话
- 86-73182287663
- 手机号
- 13907487460
- 总经理
- 李欣春 请说明来自顺企网,优惠更多
- 让卖家联系我
产品详细介绍
主要成分 | Kavlactones | 提取来源 | 卡瓦根 |
外观 | 浅黄至浅棕黄色 | 检测方法 | HPLC |
含量 | 30(%) | 应用剂型 | 胶囊、片剂、汀剂 |
临床应用 | 抗忧郁 | 包装 | 25KG/桶 |
保存期 | 24(月) |
product name
|
kava kava root extract | ||
latin name
|
piper methysticum forst | ||
plant part used
|
root | ||
active ingredient
|
kavalactones (mainly including: kavain, dihydrokavain, desmethoxyyangonin... | ||
specification
|
30% kavalactones hplc | ||
test method
|
hplc | ||
case no
|
500-64-1 | ||
main function
|
anti-depression, relieves insomnia and promotes sleep |
brief introduction
synonyms--- kava, awa, ava, yaqona, sakau
kavain
(kawain)
chemical
name:2r)-4-methoxy-2-[(e)-2-phenylethenyl]-2,3-dihydropyran-6-one
molecular
formula:c14h14o3
mol.
wt.:230.26
molecular
structure:
kava kaka,
or kava, (piper methysticum) (piper latin for "pepper", methysticum
greek for "intoxicating") is an ancient crop of the south pacific.
the word kava is used to refer both to the plant and the beverage
produced from its roots. kava has been used by indigenous people as
an intoxicating traditional beverage since ancient times. various
preparations of kava have been marketed since the 1980s, especially
in europe and north america to manage mild anxiety, tension, and
restlessness. some reports also indicate that kava preparations may
have analgesic, spasmolytic, neuroprotective, and antimitotic
activities.
its active ingredients are called kavalactones. to date, 18
kavalactones have been identified, among these, six major
kavalactones constitute approximately 95% of the lipid extract
derived from the dried roots and rhizomes; these are kavain,
dihydrokavain, methysticin, dihydromethysticin, yangonin, and
desmethoxyyangonin.
safety concerns have been raised over liver toxicity largely due to
the use of stems and leaves by supplement makers, as opposed to
solely the root of the plant as dictated by
traditional uses.
the kava kava root extract used in dietary supplements is derived
from the roots (not including the stems and leaves) of the plant
piper methysticum.
benefits
• relieves mild to moderate depression
• relieves insomnia and promotes sleep
• mental support
• analgesic and spasmolytic effects (reduces overall sensation of
pain)
• neuroprotective
• antimitotic
• anticancer effects
mechanism
effects of kavalactones include mild sedation, a slight numbing of
the gums and mouth, and vivid dreams. kava has been reported to
improve cognitive performance and promote a cheerful mood. muscle
relaxant, anaesthetic, anticonvulsive and anxiolytic effects are
thought to result from direct interactions of kavalactones with
voltage-gated ion channels. research currently suggests that
kavalactones potentiate gabaa activity but do not alter levels of
dopamine and serotonin in the cns. heavy, long-term kava use does
not cause any reduction of ability in saccade and cognitive tests
but is associated with elevated liver enzymes.
desmethoxyyangonin, one of the six major kavalactones, is a
reversible mao-b inhibitor (ki 280 nm) and is able to increase
dopamine levels in the nucleus accumbens. this finding might
correspond to the slightly euphoric action of kava.[10]
kavain, in both enantiomeric forms, inhibits the reuptake of
noradrenalin at the transporter (nat), but not of serotonin (sert).
an elevated extracellular na level in the brain may account for the
reported enhancement of attention and focus.
safety
kava kava root extract (solely root, no stem and leaves) is
safe.
the kava extracts with stems and leaves are of liver damage.
chronic and heavy use of kava for a period of three months or more
has occasionally been reported to cause a scaly, yellow skin rash
and an eye irritation that disappears after discontinuation of the
herb.
dosage
• the typical dose is 200-500mg per day (usually in 2-3 doses
throughout the day).
• consult physicians for different condition specifics.
gni’s kava kava root
extract features and benefits:
kava kava root extract is one of gni"s important products, with
many advantages as list in the following, produced as our
patent-pending process and know-how technology from piper
methysticum roots only.
• produced with pure water only
• high purity: over 30%
• no solvent - residual free
• pesticide-free
• natural yellow or light yellow-brown in appearance
• high anti-bacteria, and longer shelf life
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