| 中文名 | 17α-羟基黄体酮
|
| 英文名 | 17A-hydroxyprogesterone
|
| 别名 | 羟孕酮
羟基孕酮
17羟孕酮
羟基黄体酮
17-羟基妊娠素
17α-羟基黄体酮
17Α-羟基孕甾酮
17Α-羟基黄体激素
17Α-羟基孕烯二酮
|
| 英文别名 |
prodix
prodox
gestagenogador
Hydroxyprogesterone
17a-Hydroxyprogesterone
17A-hydroxyprogesterone
17alpha-Hydroxyprogesterone
4-Pregnen-17a-ol-3,20-dione
17-Alpha-Hydroxy-Progesterone
17-Hydroxypregn-4-en-3,20-dione
17-hydroxy-pregn-4-ene-20-dione
17-hydroxypregn-4-ene-3,20-dione
17a-Hydroxypregn-4-ene-3,20-dione
17-alpha-hydroxypregn-4-ene-3,20-dione
delta(4)-pregnene-17alpha-ol-3,20-dione
(8R,9S,10R,13S,14S,17R)-17-ACETYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
|
| CAS | 68-96-2
|
| EINECS | 200-699-4 |
| 化学式 | C21H30O3
|
| 分子量 | 330.46 |
| InChI | InChI=1/C21H30O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h12,16-18,24H,4-11H2,1-3H3 |
| 密度 | 1.0998 (rough estimate) |
| 熔点 | 276°C |
| 沸点 | 407.89°C (rough estimate) |
| 闪点 | 9℃ |
| 水溶性 | 5.056mg/L(20 C) |
| 蒸汽压 | 2.37E-11mmHg at 25°C |
| 溶解度 | soluble in Chloroform |
| 折射率 | 90 ° (C=1, CHCl3) |
| 酸度系数 | 13.03±0.60(Predicted) |
| 存储条件 | Sealed in dry,Room Temperature |
| 外观 | neat |
| 颜色 | White to Almost white |
| Merck | 14,4839 |
| BRN | 3218109 |
| 物化性质 | 结晶（丙酮/己烷）。熔点221℃（219-220℃）。[α]20/D+97°（氯仿）。 |
| 产品用途 | 用作甾体激素药中间体 |
| 体外研究 | 17α-OHP是一种类似于孕酮的孕激素受体激动剂，虽然效果比较弱。它还是一种在类固醇激素如雄性激素、雌性激素性激素、糖皮质激素、盐皮质激素的生物合成过程中的化学中间体。 |
| 体内研究 | 17-Hydroxyprogesterone 是一个有效的GVBD（生殖泡破裂）的类固醇诱导剂。 |